Average Principal Scientist with Biotechnology Skills Salary in South San Francisco, California

$145,872
Avg. Base Salary (USD)
25%
$132k
MEDIAN
$146k
75%
$160k

The average salary for a Principal Scientist is $145,872 in 2025

Base Salary
$132k - $160k
Bonus
$6k - $21k
Total Pay
$143k - $182k
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FAQs About Principal Scientists

What is the highest pay for Principal Scientists in South San Francisco?

Our data indicates that the highest pay for a Principal Scientist in South San Francisco is $NaN / year

What is the lowest pay for Principal Scientists in South San Francisco?

Our data indicates that the lowest pay for a Principal Scientist in South San Francisco is $NaN / year

How can Principal Scientists increase their salary?

Increasing your pay as a Principal Scientist is possible in different ways. Change of employer: Consider a career move to a new employer that is willing to pay higher for your skills. Level of Education: Gaining advanced degrees may allow this role to increase their income potential and qualify for promotions. Managing Experience: If you are a Principal Scientist that oversees more junior Principal Scientists, this experience can increase the likelihood to earn more.