▼5%
$132,214
Avg. Base Salary (USD)
/ year
Avg. Base Salary (USD)
10%
$105k
MEDIAN
$132k
90%
$155k
The average salary for a Principal Scientist is $132,214 in 2025
Base Salary
$105k - $155k
Bonus
$6k - $21k
Profit Sharing
$0 - $2k
Total Pay
$116k - $166k
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What is the Pay by Experience Level for Principal Scientists?
What Do Principal Scientists Do?
Find your market worth – how it works:
Common Health Benefits for a Principal Scientist
Medical
94%
Dental
88%
Vision
82%
None
6%
Gender Breakdown for Principal Scientists
Female
57.1%
Male
42.9%
This data is based on 7 survey responses. Learn more about the gender pay gap.
FAQs About Principal Scientists
What is the highest pay for Principal Scientists in San Diego?
Our data indicates that the highest pay for a Principal Scientist in San Diego is $155k / year
What is the lowest pay for Principal Scientists in San Diego?
Our data indicates that the lowest pay for a Principal Scientist in San Diego is $105k / year
How can Principal Scientists increase their salary?
Increasing your pay as a Principal Scientist is possible in different ways. Change of employer: Consider a career move to a new employer that is willing to pay higher for your skills. Level of Education: Gaining advanced degrees may allow this role to increase their income potential and qualify for promotions. Managing Experience: If you are a Principal Scientist that oversees more junior Principal Scientists, this experience can increase the likelihood to earn more.